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教育培訓(xùn)行業(yè)知識(shí)型媒體
發(fā)布時(shí)間: 2023-02-10 12:40:03
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單位：化學(xué)系
職稱：特聘副研究員，碩士生導(dǎo)師
基本信息
個(gè)人簡(jiǎn)介
Research ID
http://www.researcherid.com/rid/B-6637-2011
2013.1-至今 浙江大學(xué)，化學(xué)系，特聘副研究員，碩士生導(dǎo)師
2010.6-2013.1 浙江大學(xué)，控制系，智能系統(tǒng)與控制研究所，博士后（導(dǎo)師，方群教授，牟穎教授）
2012.1-2012.4 National University of Singapore（新加坡國(guó)立大學(xué)），化學(xué)系，訪問(wèn)學(xué)者（合作導(dǎo)師，Prof. Shaoqin Yao）
2005.9-2010.6 浙江大學(xué)，化學(xué)系，微分析系統(tǒng)研究所，博士（導(dǎo)師，方群教授）
2001.9-2005.6 浙江大學(xué)，化學(xué)系，學(xué)士
工作研究領(lǐng)域
（1）超微量、高通量的微流控篩選儀器，并用于藥物篩選和蛋白質(zhì)結(jié)晶篩選；
（2）新型微型化電噴霧質(zhì)譜離子源的研制以及用于藥物篩選和單細(xì)胞分析；
（3）基于激光誘導(dǎo)熒光的單分子和單細(xì)胞分析方法；
（4）基于微流控芯片的微型化色譜分離和檢測(cè)裝置。
聯(lián)系方式
電話：+86+57188206771
電子信箱：yingzhu#zju.edu.cn
研究成果
1. 超微量、高通量微流控液體操縱和檢測(cè)裝置
研制了一種基于液滴微流控技術(shù)的全自動(dòng)液體操縱和檢測(cè)裝置。該裝置可高度可靠的進(jìn)行皮升級(jí)液體定量量取、混合、轉(zhuǎn)移、檢測(cè)、以及生化篩選。與常規(guī)基于384孔板的篩選系統(tǒng)相比，其試樣消耗降低了37000倍以上。目前，該裝置獲得了2011年度浙江大學(xué)自研自制儀器設(shè)備優(yōu)秀成果獎(jiǎng)。
實(shí)驗(yàn)室介紹
浙江大學(xué)紫金港校區(qū)化學(xué)樓101 房間（Lab）
浙江大學(xué)紫金港校區(qū)化學(xué)樓104房間（Office）
發(fā)表論文
2013
[1] Yingzhu,Yunxia Zhang,Longfei Cai,Qun Fang,Sequential Operation Droplet Array: An Automated Microfluidic Platform for Picoliter-Scale Liquid Handling,Analysis,and Screening,Analytical Chemistry,2013,85(14): 6723–6731 fck_filebrowser.php
[2] Ying Zhu,* Nian-Nian Chen,* Qi Li,Qun Fang,Improving the sensitivity of confocal laser induced fluorescence detection to sub-picomolar scale for round capillaries by laterally shifting laser focus point,Analyst,2013,138,4642-4648fck_filebrowser.php (*coauthors)
[3] Ying Zhu,Qun Fang,Analytical detection techniques for droplet microfluidics—A review,Analytica Chimica Acta,2013,787,24-35 fck_filebrowser.php
[4] Yuan Su,Ying Zhu,Qun Fang,A multifunctional microfluidic droplet-array chip for analysis by electrospray ionization mass spectrometry,Lab on a Chip,2013,13(10),1876-1882
[5] Qi Li,Ting Zhang,Ying Zhu,Qun Fang,Automated high-speed CE system for multiple samples,Electrophoresis,2013,34(4),557-561
2012
[1]Ying Zhu,Hong Chen,Guansheng Du,Qun Fang. Microfluidic Droplet-Array Liquid-Liquid Chromatography based on Droplet Trapping Technique. Lab on a Chip,2012,12(21): 4350–4354fck_filebrowser.php
[2]Long-fei Cai,* Ying Zhu,* Qun Fang,Droplet-based Microfluidic Flow Injection System with Large-Scale Concentration Gradient by a Single Nanoliter-Scale Injection for Enzyme Inhibition Assay,Analytical Chemistry,2012,84(1): 446-452 (*同等貢獻(xiàn))fck_filebrowser.php
[3] Xiuli Wang,Ying Zhu,Qun Fang,Valveless gated injection for microfluidic chip-based liquid chromatography system with polymer monolithic column,Journal of Chromatography A,2013,1246,123-128
[4]Ji-feng Fan,Ying Zhu,Xiao-tong Shi,Qun Fang,Jiang Huang,Microfluidic sequential injection analysis system based on polydimethylsiloxane (PDMS) chip with integrated pneumatic-actuated valves,Science china-chemistry,2012,55(4): 531-536
2011
[1]Yun-xia Zhang,* Ying Zhu,* Bo Yao,Qun Fang. Droplet Array for Real Time Reverse Transcription Polymerase Chain Reaction,Lab on a Chip,2011,11(8):1545-1559 (*同等貢獻(xiàn))
[2]Ze-Qi Yu,Ying Zhu,Yunxia Zhang,Juan Li,Qun Fanga,Jianzhong Xi,Bo Yao,Nanoliter droplet array for microRNA detection based on enzymatic stem-loop probes ligation and SYBR Green real-time PCR,Talanta,2011,85 (4): 1760-1765
[3]Shu-Qing Gu,Yun-Xia Zhang,Ying Zhu,Wen-Bin Du,Bo Yao,Qun Fang,Multifunctional picoliter droplet manipulation platform and its application in single cell analysis. Analytical Chemistry,2011,83(19):7570-7576
[4]Xin-Jue Wang,Ying Zhu,Qun Fang,Developments and applications of microfluidic chip-based chromatographic technique,Chinese Journal of Chromatography,2011,29(2): 99-104
2010
[1]Ying Zhu,Qun Fang. Integrated Droplet Analysis System with Electrospray Ionization-Mass Spectrometry Using a Hydrophilic Tongue-based Droplet Extraction Interface. Analytical Chemistry,2010,82(19): 8361-8366fck_filebrowser.php
[2]Ying Zhu,Jian-zhang Pan,Yuan Su,Qiao-hong He,Qun Fang. Fabrication of Low-Melting-Point Alloy Microelectrode and Monolithic Spray Tip for Integration of Glass Chip with Electrospray Ionization Mass Spectrometry. Talanta,2010,81(3):1069-1075fck_filebrowser.php
[3]Wen-bin Du,* Meng Sun,* Shu-qing Gu,* Ying Zhu,* Fang Qun. Automated Microfluidic Screening Assay Platform based on DropLab. Analytical Chemistry,2010,82(23): 9941-9947 (*同等貢獻(xiàn)）
[4]Qing-Hu Lin,Yong-Qiang Cheng,Ya-Ni Dong,Ying Zhu,Jian-Zhang Pan,Qun Fang,High-speed separation of proteins by sodium dodecyl sulfate-capillary gel electrophoresis with partial translational spontaneous sample injection,Electrophoresis,2011,32(20): 2898-2903
會(huì)議論文
[1]Qun Fang,Ying Zhu,Hong Chen. Microfluidic chip-based droplet-array liquid-liquid chromatography. Proceedings of the First Shenyang International Colloquium on Microfluidics. Shenyang,China,2007,256~258（報(bào)展）
[2]Ying Zhu,Jian-Zhang Pan,Yuan Su,Qun Fang. A microfluidic chip based electrospray interface for mass spectrometry with a low-temperature alloy microelectrode. Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences. San Diego,USA,2008,976~978（報(bào)展）
[3]Ying Zhu,Hong Chen,Qun Fang. Droplet-array liquid chromatography on a microfluidic chip using droplet trapping technique. The 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Kyoto,Japan,2008,147 （口頭報(bào)告）
[4]Ying Zhu,Jian-Zhang Pan,Yuan Su,Qun Fang. A novel interface for electrospray ionization mass spectrometry on a microfluidic glass chip. The 5th National Conference on Micro-Total Analytical Systems,Nanjing,China,2008,188（報(bào)展）
[5]Ying Zhu,Hong Chen,Qun Fang. Droplet-array liquid chromatography on a microchip. Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Jeju,Korea,2009,1470~1472（報(bào)展）
[6]Ying Zhu,Qun Fang. Droplet analysis with electrospray ionization mass spectrometry using an integrated glass microchip,Fourteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Groningen,The Netherlands,2010,1352~1354 (口頭報(bào)告)
[7]Ying Zhu,Qun Fang,Integrated microfluidic chip for droplet analysis based on electrospray ionization mass spectrometry,The 6th National Conference on Micro-Total Analytical Systems,Shanghai,China,2010（報(bào)展）
[8]Yuan Su,Ying Zhu,Qun Fang,A multifunctional microfluidic droplet array system with ESI-MS detection,Fifteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Seattle,USA,2011,586~589（報(bào)展）
[9]Yun-Xia Zhang,Ying Zhu,Bo Yao,Qun Fang. Nanoliter droplet array for digital PCR. The 37rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Dalian,2011,316（報(bào)展）
[10]Xiu-Li Wang,Ying Zhu,Qun Fang. Microchip-based valveless high performance liquid chromatography system with gated injection. The 37rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Dalian,2011,315（報(bào)展）
[11]Ying Zhu,Yunxia Zhang,Longfei Cai,Qun Fang,High throughput and picoliter-scale drug screening with automated droplet microarray system,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,389-391（報(bào)展）
[12]Yun-Xia Zhang,Ying Zhu,Qun Fang,Bo Yao,Single cell microRNA quantification with two step RT-Q-PCR based on flexible nanoliter-scale droplet array system,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,428-430（報(bào)展）
[13]Xiu-Li Wang,Ying Zhu,Qun Fang,Droplet analysis system using liquid chromatography and mass spectrometry for enzyme inhibition assay,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,1921-1923（報(bào)展）
[14]Li-na Zhu,Ying Zhu,Qun Fang Nanoliter-Scale Screening of Protein Crystallization with Sequential Operation Droplet Array,The 5th International Symposium on Microchemistry and Microsystems,Xiamen,China,2013 （報(bào)展,CHEMINAS POSTER AWARD）
[15]Ying Zhu,Nian-nian Chen,Qi Li,and Qun Fang,Laterally Shifting Laser Focus Point on Round Capillary can Improve the Sensitivity of Confocal Laser Induced Fluorescence Detection to Sub-picomolar Scale,The 5th International Symposium on Microchemistry and Microsystems,Xiamen,China,2013 （口頭報(bào)告）
研究生招生
每年招收碩士生2~3名，博士生1~2名，歡迎對(duì)分析儀器研制、微流控分析新方法、質(zhì)譜分析學(xué)研究有興趣的同學(xué)報(bào)考
正在進(jìn)行的研究項(xiàng)目
1．多通道微量液滴點(diǎn)樣儀的研制
2．高通量電噴霧質(zhì)譜分析系統(tǒng)的研究
3．蛋白質(zhì)結(jié)晶新方法研究
*如果發(fā)現(xiàn)導(dǎo)師信息存在錯(cuò)誤或者偏差，歡迎隨時(shí)與我們聯(lián)系，以便進(jìn)行更新完善。
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